The following year Luny Tunes continued to further their reputation, establishing themselves as bona fide hitmakers when "Gasolina," one of their numerous productions featured on Daddy Yankee's Barrio Fino (2004), became a worldwide hit and club anthem. In addition to Barrio Fino, Luny Tunes also contributed productions to acclaimed albums by Don Omar (The Last Don, 2003) and Tego Calderón (El Abayarde, 2003), as well as albums by Eddie Dee (12 Discipulos, 2004), Ivy Queen (Diva, 2004), Zion & Lennox (Motivando a la Yal, 2004), Nicky Jam (Vida Escante, 2004), and Trebol Clan (Los Bacatranes, 2004) -- all of this within a two-year span.
In 2005, Luny Tunes released Mas Flow, Vol. 2, their first all-new album since the previous volume, and in 2006 they released a third, Mas Flow: Los Benjamins, along with a second compilation of previously released material, Reggaeton Hits, which had been preceded by a prior best-of collection, La Trayectoria (2004). The next mixtape dropped in 2007, Los Benjamins: La Continuacion, not long after the duo's second volume in the Kings of the Beats instrumental series. By this point, Luny Tunes were employing various assistant producers (Tainy, Jose M. Gomez, Nely, Los Presidents, Mr. G, et al.), who were employed as part of the Mas Flow Inc. production factory. ~ Jason Birchmeier